It revealed that there was significant difference in decreasing ALT level between the SIL treating group and control group, which suggested SIL could also play a pivotal role in hepatic protection by reducing ALT level in serum (ALT UI/L: MD = −9.16; 95% CI, −16.24 to −2.08; P = .01) (Fig. 3). Here, GPT is linked to squamous cell intraepithelial neoplasia.