It was observed that SIL could relatively revive the liver by lowering not only the AST level but also ALT level comparing to controlled regimens, which was in accordance with previous researches.[12,26] Additionally, regarding to AST and ALT level, the SIL monotherapy group could have attained more robust therapeutic efficacy than SIL combination group (AST UI/L: MD = -8.48; 95% CI, 19.93 to −2.97, P = .15; ALT UI/L: MD = −14.31; 95% CI, −29.51 to 0.90; P = .07). Here, GPT is linked to squamous cell intraepithelial neoplasia.