Recently, SIL extract tablets treated fatty liver disease in several clinical trials, whose results showing decreased hepatic enzymes levels in serum, especially ALT, indicated that SIL could partially restore the liver's function and mitigated NASH patients’ symptoms.[11] Furthermore, there were few side effects when administrating with therapeutic dosage.[12] Therefore, SIL could be a promising herbal regimen to treat NAFLD patients. The gene discussed is GPT; the disease is metabolic dysfunction-associated steatotic liver disease.