Infection with OV-IA82-Δ119 and OV-IA82-RV119LxGxE-Flag but not OV-IA82 or OV-IA82-RV119Flag led to rapid nuclear translocation of NF-κB-p65 as early as 30 min p.i. (Fig 4B and 4C). Here, NFKB1 is linked to infection.