FOXJ1 and Hydrocephalus: As noted above, 19% of FOXJ1-Cre;CEP164fl/fl mice displayed severe hydrocephalus with a prominently domed head around weaning (11 out of 58 mice) (Fig 2B, left panels); however, all FOXJ1-Cre;CEP164fl/fl adult mice examined (n = 10) showed substantial ventricular enlargement (middle panels).