However, despite significantly increased expression of the proposed 60 kDa form of SCARF-1 within chronically diseased liver tissue sections (Fig. 1a), there were no significant differences in sSCARF-1 concentrations in serum from patients with chronic liver disease (PSC and PBC) compared to healthy donor controls (Fig. 1c). The gene discussed is SCARF1; the disease is primary biliary cholangitis.