SYK and cancer: In our integrated miRNA−mRNA analysis miR-129-5p was predicted to target several oncogenes that included IRF4, PIM1, FOXP1, SYK, BCL10, RUNX1, and ABL1. These were enriched for cancer-associated pathways, such as regulation of I-kappaB kinase/NF-kappaB cascade, regulation of protein kinase cascade, cell death, and apoptosis (not shown).