NR3C1 and lung carcinoma: The time course of Fkbp5 mRNA induction in BMDMs is shown in Figure 1A. In human A549 lung carcinoma cells, GR binding sites have been described 34 kb 5′ and 87 kb 3′ of the FKBP5 transcription start site (TSS) (Reddy et al., 2009).