REN and Pleural effusion: In addition, in mice with vs. without ovariectomy, there were no significant differences in pleural effusions (3 out of 17 vs 4 out of 10 mice), LW/BW% (Fig 5C), HW/BW% (Fig 5D), active renin plasma levels (P>0.05, n = 8 per group) and cGMP plasma levels (P>0.05, n = 10 per group).