Autosomal-recessive fibrinogen deficiency appears to be virtually absent in Ashkenazi Jews (no mutations found in FGA and FGB; prevalence for FGG of 1.64 per 106 individuals), whereas, non-Finnish Europeans have a predicted exceptional rate of 23.05 per 106 individuals for the sole FGG gene. This evidence concerns the gene FGB and congenital afibrinogenemia.