Conversely, 81 lncRNAs appeared preferentially cytoplasmic (Figure 2D, bottom left); these include the known cytoplasmic lncRNA SNHG5, a modulator of staufen-mediated decay that influences colorectal tumor growth (Derrien et al., 2012; Damas et al., 2016) (Figure 2D, bottom right). This evidence concerns the gene SNHG5 and colorectal neoplasm.