SERPINH1 and intraepithelial neoplasia: SERPINH1/HSP47 is extensively expressed in the intratumoral and peritumoral stroma/fibrotic areas of pancreatic cancer samples; the link between SERPINH1/HSP47 expression and pancreatic cancer development is further evidenced by the observation that SERPINH1/HSP47 is progressively up‐regulated from noninvasive pancreatic to intraepithelial neoplasia 20.