HOTTIP and pancreatic neoplasm: The high expression level of lncRNA BC008363 had significantly better survival rates.35 A more recent study reported that the lncRNA HOTTIP/HOXA13 played a potential therapeutic target and molecular biomarker for PDAC.36 Therefore, in an attempt to decrease mortality and improve prognosis of PDCA, a molecular screening biomarker at an early stage of pancreatic cancer is in urgent need.