RECQL4 and diabetes mellitus: Furthermore, there are other Mendelian syndromes with mutations in DNA repair genes that characteristically show adult noncommunicable diseases but do not have IUGR; such is the case for Werner syndrome, a progeroid disease caused by biallelic mutations in another RecQ helicase (RecQ4) that clinically presents with postnatal short stature and a prevalence of type 2 diabetes mellitus of 70% [50, 70, 74].