PAEP and endometrium adenocarcinoma: Glycodelin is upregulated by HDACIs, trichostatin A, and suberoyl anilide hydroxamic acid, which further speeds the migration of Ishikawa endometrial adenocarcinoma cells (98) but promotes cell differentiation to the normal epithelium characteristics (99), which generates a dilemma in the clinical use of HDACIs for anticancer treatment.