PTX3 and Ito hypomelanosis: We analyzed cytokine data according to the genotypes of two of the most robust genetic markers for IPA identified to date, rs2305619 in PTX3 (Cunha et al., 2014, 2015; Wojtowicz et al., 2015) and rs16910526 in CLEC7A (Cunha et al., 2010; Chai et al., 2011).