The transcriptional activity of AQP4-M1 was found to be repressed by microRNA-130a (miR-130a), which may result in the reduction of AQP4-M1/M23 ratio, in Astrocytoma (CRL1718) and HeLa (CCL2) cells (Sepramaniam et al., 2012). Here, AQP4 is linked to astrocytoma (excluding glioblastoma).