RIPK3 and infection: There was clear evidence of MLKL phosphorylation 72 h following dl922-947 infection in the presence of zVAD.fmk (Fig. 6c) but not at 24 or 48 h (Fig. S14), and the effect of zVAD.fmk was partially rescued by the RIPK3 inhibitor GSK2791840B (Fig. 6d).