We introduce here new high-affinity chemical dye baits that bind the following well-characterized TB antigens and inflammatory markers: (i) LAM, (ii) early secretory antigenic target 6 (ESAT6) (11), (iii) culture filtrate protein 10 (CFP10) (11), and (iv) inflammatory cytokines nonspecifically associated with an active infection including interleukin-2 (IL-2), interferon-γ (IFN-γ), and tumor necrosis factor–α (TNFα) (12). The gene discussed is TNF; the disease is infection.