We also know thatsystematically avoiding hyperglycemia through the implementation of continuouscorrection therapy with insulin significantly reduces the risk of developingICU-acquired weakness as well as the days of invasive MV and the length of stay inthe ICU.(35,36) The observed relationship between insulin therapyand the lower development of ICU-acquired weakness might justify the associationbetween hyperglycemia and the increased risk for developing ICU-acquired weaknessobserved among our patients. The gene discussed is INS; the disease is Hyperglycemia.