GAD2 and type 1 diabetes mellitus: Moreover, percentages of CD3-CD8dullCD56+ILT2+ NK cells were significantly increased in T1D patients vs controls (Fig 3A and 3C, KS test<0.05; Unpaired t test with Welch's correction, p = 0.0461) indicating that in T1D samples, the NK cell subset preferentially binds the HLA class I GAD65 AA 114–122 pentamer through ILT2 receptor.