Change in DAS28(CRP) after 14 weeks of infliximab treatment correlated with change in synovial Ktrans in the MCPs (0.33 (0.03; 058) but not the wrist and similarly with change in RAMRIS-synovitis in the MCPs (0.39 (0.10–0.62)) but not the wrist. This evidence concerns the gene CRP and synovitis.