At baseline, DAS28(CRP) correlated significantly with synovial Ktrans in the wrist (Pearson correlation coefficient (90% CI) = 0.39 (0.19–0.55)) and MCPs (0.36 (0.16–0.53)) and with RAMRIS-synovitis in the wrist (0.29 (0.08–0.47)) and MCPs (0.54 (0.37–0.67)). The gene discussed is CRP; the disease is synovitis.