A previously published study from this laboratory showed an increase of a CD44high expressing cell population in docetaxel‐resistant PC3 cells.27 This coincided with increased expression of the cancer stem cell (CSC)‐like marker CD49b.28 We therefore investigated the expression of CD24 (a marker for low‐differentiated to full‐differentiated, luminal prostate cells29, 30), CD44, and CD49b after long‐term IL‐4 treatment. Here, IL4 is linked to cancer.