IL4 and posterior cortical atrophy: Morphological changes of PCa cell lines after long‐term cytokine treatment have previously been observed.25, 26 Microscopic phase‐contrast analysis of the long‐term IL‐4‐treated PC3 (PC3‐IL4) cells revealed clonal outgrowths of cuboid‐shaped cells with increased size and light absorbance properties residing within the morphologically normal PC3 cell population (Figure 2).