As shown in Fig. 1a–c, the B7-H4 expression in tumor tissues was much higher than that in adjacent non-tumor tissues (messenger RNA, 1.65 ± 0.21 vs. 0.51 ± 0.13 and protein, 1.81 ± 0.42 vs. 0.43 ± 0.11, p < 0.05, respectively). Here, VTCN1 is linked to neoplasm.