Then, we dichotomized whole cohort into B7-H4high (the combined score for B7-H4 expression >3 points; n = 63) and B7-H4low (the combined score for B7-H4 expression ≤3 points; n = 77) subgroup, and analyzed the relationship between the level of B7-H4 expression and clinicopathological features of ICC (Table 1). This evidence concerns the gene VTCN1 and intrahepatic cholangiocarcinoma.