When we assessed for spontaneous Th1 cytokine secretion, on average, CD4+ T cells purified from sarcoidosis PBMC secreted nearly 5-fold higher levels of IL-2 (Figure 1(a); 43.6 pg/mL versus 8.97 pg/mL, p < 0.0001) and more than 2-fold higher levels of IFN-γ (Figure 1(b); 55.8 pg/mL versus 20.95 pg/mL, p < 0.01) than those purified from healthy controls, findings consistent with previous investigations [18]. This evidence concerns the gene CD4 and sarcoidosis.