SIRT6 and melanoma: As the first step of our investigation into understanding the role of SIRT6 in melanoma, we determined the expression profile of SIRT6 in normal human epidermal melanocytes (NHEM) and a panel of human melanoma cell lines (A375, Hs 294T, G361, SK-MEL-2, SK-MEL-28, WM35, WM115 and 451Lu).