To explore the genes most closely related to gan-shen Yin deficiency, we measured the transcriptional expression of these 17 mRNA variables in 25 PLC samples, 44 HBP samples and 50 DM samples from gan-shen Yin deficiency groups and 25 PLC samples, 50 HBP samples, and 50 DM samples from non-gan-shen Yin deficiency groups. This evidence concerns the gene HSPG2 and diabetes mellitus.