EZH2 overexpression is frequent in tumor cells and in vessels of human epithelial ovarian cancers and is associated with poor prognosis.31 Vessels of human healthy ovarian tissue presented very low EZH2 expression, while VEC, Claudin-5, and PECAM1 were clearly detectable (Figure 8B, upper). The gene discussed is PECAM1; the disease is ovarian carcinoma.