ERBB2 and metastatic malignant neoplasm in the lymph nodes: HER2 overexpression was significantly related to differentiation (P = 0.01) and distant metastasis (P = 0.045), but not associated with the remaining clinicopathological variables, including depth of invasion (P = 0.47), lymph node metastasis (P = 0.98) and TNM stage (P = 0.16).