The HER family is composed of four members, including EGFR/HER1/ErbB1, HER2/ErbB2, HER3/ErbB3, and HER4/ErbB4 [6], and plays a key role in the pathogenesis of various human solid tumors, including breast, gastric and lung cancers [7]. The gene discussed is ERBB4; the disease is lung carcinoma.