NPPB and heart failure: But, the increase in LA maximum and minimal volumes (as well as their indexes to BSA: LAVImax and LAVImin) in our patients do not seem to rely on a remarkable progression of conditions with heart failure, since the LVEF, NT-proBNP levels or the covered distances at the 6 min walk test did not significantly change 6 weeks or 6 months after interventional LAA closure.