FBF1 and neoplasm: In an attempt to see their FBF-independent function, we tested fbf-1 fbf-2 sygl-1(ubiq) and fbf-1 fbf-2 lst-1(ubiq) animals for tumor formation at 25°C, because at this temperature, the FBF requirement is relieved in that fbf-1 fbf-2 mutants can maintain a small GSC pool [40].