No correlation was observed between syndecan-4 concentrations and myocardial fibrosis, with a mean syndecan-4 concentration of 14.9 ± 5.8 ng/ml in subjects with DE versus 16.8 ± 10.2 ng/ml in subjects without DE (P = 0.386; Fig 1). Here, SDC4 is linked to Myocardial fibrosis.