MYC and cancer: Among those genes the proto-oncogene c-MYC, located 330 kb away from SNP rs6983267, has been implicated in human cancers by influencing several important cellular functions including: the cell cycle, apoptosis, signal transduction, transcriptional and post-transcriptional regulatory mechanisms, non-coding RNAs, stem cell biology, chromosomal translocation and gene amplification [28].