Mechanistic analysis of the Warburg effect in HCT116 colorectal cancer cells identified decreased intracellular carnitine levels relative to noncancerous fetal human colonocytes [96]; additionally, Western blotting revealed decreased expression of organic cation/carnitine transporter 2 (OCTN2), a sodium-coupled cotransporter for carnitine, in the HCT116 cell line [96]. Here, SLC22A5 is linked to colorectal cancer.