The epidermal growth factor receptor (EGFR)-mediated miRNA miR-7 is a known key player in multiple lung-related diseases and has previously been proposed as a biomarker in serum for chronic obstructive pulmonary disease and is thought to act by suppressing the coupling of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (SMARCD1) with p53 [101,102]. Here, SMARCA1 is linked to chronic obstructive pulmonary disease.