DIAPH1 and viral infectious disease: Although viral infection immediately after CHX addition did not accelerate DIAP1 depletion (Figure 3—figure supplement 1A, lanes 1 and 2 vs. 3 and 4), viral infection before CHX addition did promote DIAP1 degradation (Figure 3—figure supplement 1A, lanes 5 and 6, 1B, 1C, and 1D).