They observed a strong positive correlation between total sugar uptake and GLUT1 expression and an inverse correlation between total sugar uptake and both mTOR expression and IGF-1 expression, and it is well-known that IGF-1 signaling is inhibited in IUGR (Laviola et al., 2005; Street et al., 2011). The gene discussed is IGF1; the disease is fetal growth restriction.