HOXA13 and hand-foot-genital syndrome: Moreover, several nonsense mutations (p.W369X, p.S136X, p.Q196X, and p.Q365X), missense mutations within the homeodomain (p.I368F, p.N372H and p.V375F), and in-frame polyalanine expansions of HOXA13 gene have been found to cause Müllerian duct fusion defects in patients with hand-foot-genital syndrome [14, 30–32].