Conversely, MMC samples from the high-risk group were characterized by a significant enrichment of genes related to undifferentiated plasmablasts (MOREAUX MULTIPLE MYELOMA BY TACI DN, P<0.0001), MYC target genes (SCHLOSSER MYC TARGETS REPRESSED BY SERUM, P=0.01) and the myeloma CD1 molecular subgroup (ZHAN MULTIPLE MYELOMA CD1 UP, P=0.01) (Supplementary Figure 6B). The gene discussed is TNFRSF13B; the disease is plasma cell myeloma.