Gene expression profiles of VP-treated GC cell lines revealed that cancer-associated genes such as FAT1 [27], IGF2R [17], CDH17 [12], MUC1 [18], ALCAM [24], ITGB1 [7], ERBB3 and ITGAV were altered, suggesting that VP suppresses oncogenic potential. This evidence concerns the gene ITGB1 and cancer.