BCR and leukemia: Resembling mice with Hoxa9+BCR/ABL and Hoxa10+BCR/ABL leukemias, the bone marrow, spleen and liver of the moribund mice were infiltrated by immature leukemia blasts (Figure 5B and 5D), representing 31 ± 5.7% (Mean ± SD) of all nucleated cells in the bone marrow.