Several SNPs of the well-known CRC susceptibility loci on chromosome 8 showed differentially distributed genotypes, among them rs16892766 on 8q23.3 (P(Avs.CD)=5.48×10-4, EIF3H), rs10505477 on 8q24.21 (P(Avs.C)=6.08×10-4, CASC8), and rs6983267 also located on 8q24.21 (P(Avs.C)=7.35×10-4, MYC). This evidence concerns the gene CASC8 and colorectal carcinoma.