Furthermore, the KEGG pathway analysis revealed that a large number of enriched genes were mainly involved in carcinogenic signaling pathways, such as DNA mismatch repair (ko03430), acute myeloid leukemia (ko05221), p53 signaling pathway (ko04115), Wnt signaling pathway (ko04310), TGF-beta (transforming growth factor-β) signaling pathway (ko04350), pathways in cancer (ko05200) and so on (Figure 6B). This evidence concerns the gene TP53 and cancer.