Hence, LDs accumulation is considered as a hallmark of apoptosis [93], and this phenomenon is observed in different metabolic diseases [94, 95], induced by various forms of stress stimuli including mitochondrial dysfunction and oxidative stress [93, 96], ER stress [97, 98], osmotic stress [99], inhibition of MYC in cancer cells [100], and activation of TOR pathway [101]. Here, MYC is linked to metabolic disease.