CSF3 and metabolic dysfunction-associated steatotic liver disease: First, our data showed that hepatotropic dose G-CSF (twice a week) could improve inflammation and hepatocyte apoptosis in NAFLD for the first time, but the effects of G-CSF seem not so different in each group G1 (once a week), G2 (five days), and G3 (twice a week), and there was only a small effect.