Additionally, 335 peptides of 186 proteins were mutated exclusively in GBM tissue (mutation rate 100%), of which, 150 (80.6%) had only a single SAAV, 20 (10.8%) had 2 SAAVs, 13 (7.0%) had 2-10 SAAVs and 3 (1.6%) had more than 10 SAAVs (MYH11, 48 SAAVs; FN1, 16 SAAVs; SYNM, 14 SAAVs) (Figure 4C-4D). The gene discussed is SYNM; the disease is glioblastoma.