Overlapping molecules in two groups included up-regulated transforming growth factor beta induced (TGFBI) [9] and Nestin (NES) [10]; and down-regulated synuclein alpha (SNCA) [11] and heat shock protein family A member 12A (HSPA12A), which have demonstrated roles in GBM and/or other cancers. The gene discussed is NES; the disease is glioblastoma.