CYP19A1 and coronary artery disorder: Supplementary Table 1 shows that in the Uygur CAD population, SNP3(rs4646) is significantly associated with differences in estradiol, testosterone, and aromatase levels (P = 0.040, P = 0.007, and P = 0.009, respectively), and this association remained significant after adjustments for age, BMI, BUN, and glucose levels (P = 0.05, P = 0.03, and P = 0.03, respectively).