BRAF and melanoma: Although recent versions did not miss mutations in lung cancers, version 5.0.2.1 (since December 2015) did miss a 8.4% KIT p.K558_D572del (45-base deletion mutation) in a gastrointestinal stromal tumor specimen and version 5.0.4.0 (since September 2016) missed a 2.6% BRAF p.V600E in a melanoma specimen with less than 10% estimated tumor cellularity (unpublished data).