These results were complemented by Nilsson et al, who described 1410 differentially methylated CpG sites between MZ T2D discordant twins, including KCNQ1 (Potassium Channel Voltage Gated KQT-like Subfamily Q, Member 1), NOTCH2 (Neurogenic Locus Notch Homolog Protein 2), TCF7L2 (Transcription Factor 7-like 2) and THADA (Thyroid Adenoma Associated) T2D related genes [8]. This evidence concerns the gene NOTCH2 and type 2 diabetes mellitus.