For example, the proportion of antihypertensive drug use among patients with hypertension increased from 21.9% in 1998 to 54.8% in 2007, and the proportion of insulin or oral hypoglycemic drug treatment among patients with diabetes increased from 29.7% in 1998 to 57.4% in 2007 [32]. The gene discussed is INS; the disease is diabetes mellitus.