On the other hand, along with an increased percentage of differentially expressed gene sets between FGF5+/- goats and WT goats, the DEGs clustered in the pathways of viral myocarditis, cell adhesion molecules (CAMs), antigen processing and presentation, graft-versus-host disease, leishmaniosis, allograft rejection, staphylococcus aureus infection and type I diabetes mellitus were up-regulated. The gene discussed is FGF5; the disease is type 1 diabetes mellitus.