Novel gene-longevity associations included genes MICA/B (a locus previously linked to autoimmune conditions rheumatoid arthritis and multiple sclerosis), TOX, ZW10, SEMA6D, EGLN2/CYP2A6, EXOC3L2/MARK4 and C20orf187. This evidence concerns the gene EXOC3L2 and Autoimmunity.